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Novel immunotherapy approach against osteosarcoma
Overcoming osteosarcoma immunotherapy resistance through a novel, IL-12 driven approach
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Unravelling the diversity of bone tumours: investigating the differences between single cancer cells.
Unravelling the diversity of bone tumours
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Advancing the ICONIC trial: Improving outcomes through Collaboration in Osteosarcoma
Advancing the ICONIC trial: Improving outcomes through Collaboration in Osteosarcoma
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Towards precision medicine in Osteosarcoma
Developing genome-informed treatment to improve outcome in Osteosarcoma
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Kinder drugs to treat osteosarcoma
Optimisation of tumour-targeted methotrexate prodrugs for osteosarcoma
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Understanding osteosarcoma chemotherapy resistance
Cellular Dynamics of Chemotherapy Resistance in Osteosarcoma
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Searching for new drugs to treat osteosarcoma
Preclinical validation of novel compounds to treat osteosarcoma
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Developing an effective CAR T cell therapy for osteosarcoma
Towards Engineered T Cells for Osteosarcoma
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Sensitising osteosarcoma to immunotherapy
Modulation of interferon gamma-mediated signalling and immune response by fibroblast growth…
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Developing novel biomaterials for osteosarcoma and chordoma treatment
Developing novel biomaterials for osteosarcoma and chordoma treatment
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TP53 restoration using mRNA vaccine technology
TP53 restoration using mRNA vaccine technology
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Novel tissue engineering technology to facilitate Osteosarcoma Research
Bone-in-culture as an orthotopic platform for the study of patient-near tumour grafts…
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ICONIC
ICONIC – Improving Outcomes through Collaboration In Osteosarcoma
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Development of a targeted methotrexate prodrug with enhanced therapeutic index for osteosarcoma
Making methotrexate a kinder and more effective treatment for patients.
Current Research Projects
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